Alpha-lipoic acid (ALA) supplier specification
Nutrition BioTech is a bulk alpha-lipoic acid ingredient supplier and manufacturer, supplying DL-alpha-lipoic acid (thioctic acid, CAS 1077-28-7) and R-(+)-alpha-lipoic acid (CAS 1200-22-2) at 99% minimum by HPLC or titration, produced by organic synthesis, for B2B nutraceutical formulation.
Two grades are supplied: the racemic DL form, which is the standard commercial grade, and the R-(+)-single enantiomer. Alpha-lipoic acid is also a low-melting, light-sensitive material, so the practical conversation is about handling as much as assay: storage temperature, moisture control, and coating or granulation for compression lines. Every lot ships with a Certificate of Analysis stating identity, isomeric form, assay method and the specification range.
| Ingredient name | Alpha-lipoic acid — supplied as racemic DL-alpha-lipoic acid, and as R-(+)-alpha-lipoic acid |
|---|---|
| Synonyms | ALA; α-lipoic acid; thioctic acid; DL-α-lipoic acid; R-ALA; 5-(1,2-dithiolan-3-yl)pentanoic acid; 6,8-thioctic acid |
| CAS number | 1077-28-7 (racemic DL-alpha-lipoic acid) · 1200-22-2 (R-(+)-alpha-lipoic acid) |
| Molecular formula | C8H14O2S2 (both isomeric forms) |
| Molecular weight | 206.33 g/mol (both isomeric forms) |
| Assay / purity | 99% minimum by HPLC or titration. The assay method and the isomeric form are stated on the Certificate of Analysis for each lot. |
| Isomeric forms | Racemic DL-alpha-lipoic acid (CAS 1077-28-7) is the standard commercial grade. R-(+)-alpha-lipoic acid (CAS 1200-22-2), the single enantiomer, is supplied as a separate grade; specify the required form at enquiry, as the two are not interchangeable on label or on cost. |
| Production route | Organic synthesis. The racemic and the R-(+)-single-enantiomer routes are supplied as distinct grades, and the grade is stated on the specification sheet. |
| Appearance | Pale yellow crystalline powder with a characteristic sulfurous odour |
| Solubility | Practically insoluble in water; soluble in ethanol and in alkaline aqueous solutions. |
| Handling | Light- and heat-sensitive, and it can soften or clump above roughly 45 °C. Store cool, dry and protected from light; consider coating or granulation for tablet and stick-pack lines. |
| Typical applications | Capsules, tablets, granulations and powder blends for B2B nutraceutical manufacturing; commonly formulated alongside berberine, chromium and carnitine |
| Documentation | Certificate of Analysis, specification sheet, heavy metals, microbiological testing, residual solvents, allergen statement, GMO statement and stability data |
| Quality system | ISO 22000:2018, FSSC 22000, HACCP and GMP (certificates provided on request) |
| Supplier | Nutrition BioTech, 1601 W. Mission Blvd, Suite 103 (DL#29), Pomona, CA 91766, United States |
Alpha-Lipoic Acid
Metabolic antioxidant ingredient for mitochondrial, glucose-support and active-aging formulas.
Why brands ask for it
Alpha-Lipoic Acid supports formulation concepts around cellular energy, antioxidant defense and glucose metabolism. It is a familiar ingredient for brands that need a cost-effective mitochondrial support component that can be used alone or in combination with berberine, chromium, carnitine and NAD-focused ingredients.
Finished-product fit
Healthy glucose metabolism, antioxidant defense, mitochondrial energy, active aging. The strongest conversations start with format, serving size, documentation, and how the material behaves in the intended formula.
What makes the sample useful
- Redox antioxidant story
- Pairs with berberine, chromium, carnitine and NAD stacks
- Familiar consumer ingredient with broad market acceptance
Before the sample ships
- Confirm active marker, assay method, and specification range.
- Review stability expectations and storage conditions for the finished format.
- Confirm blend partners.
- Match the material to the target capsule, tablet, sachet, gummy, or powder format.
File Package
Ask for the material files that match your market, dosage form, and internal review process.
Available documents may include: COA / Specification / Allergen Statement / GMO Statement / Vegan Statement / Heavy Metals / Microbial Limits / Manufacturing Flow Chart / Residual Solvent / Country of Origin / Composition Statement.
Regulatory & Facility Support
Product-specific regulatory information may include Self-GRAS, NDI/NDIN, GRAS, ODI, or regulatory review notes, depending on the ingredient and target market.
Facility and quality system support may include Kosher, Halal, HACCP, ISO 22000, PCQI, c-GMP, NSF and other applicable certificates upon request.
