Pterostilbene 98% (StilbElite™) supplier specification
Nutrition BioTech is a bulk pterostilbene ingredient supplier and manufacturer, supplying pterostilbene (CAS 537-42-8) at 98% minimum by HPLC as StilbElite™, produced by organic synthesis, for B2B nutraceutical and cosmetic formulation.
Pterostilbene is the dimethylated stilbene analogue of resveratrol, and like resveratrol it is practically insoluble in water, so particle size, solubilisation format and blend uniformity matter alongside the 98% assay. Every lot ships with a Certificate of Analysis stating identity, HPLC assay and the assay basis.
| Ingredient name | Pterostilbene 98% — StilbElite™ |
|---|---|
| Synonyms | Pterostilbene; trans-pterostilbene; 3,5-dimethoxy-4′-hydroxystilbene; dimethylated resveratrol analogue |
| CAS number | 537-42-8 |
| Machine-readable identifiers | InChIKey VLEUZFDZJKSGMX-ONEGZZNKSA-N · PubChem CID 5281727 |
| Molecular formula | C16H16O3 |
| Molecular weight | 256.30 g/mol |
| Assay / purity | 98% minimum by HPLC, stated on the Certificate of Analysis for each lot. |
| Production route | Organic synthesis. Pterostilbene occurs naturally in blueberries and heartwood, but commercial material is synthetic; the route for the supplied lot is stated on the specification sheet. |
| Appearance | White to off-white crystalline powder |
| Solubility | Practically insoluble in water; soluble in ethanol, DMSO and propylene glycol. Solubilised and dispersible formats should be discussed for liquid and beverage systems. |
| Typical applications | Capsules, tablets, softgels and powder blends for B2B nutraceutical manufacturing, and cosmetic actives; commonly formulated alongside resveratrol, NMN and NAD+ precursors |
| Documentation | Download public specification sheet Public sheet prepared from the current product-page specification block; not a batch-specific Certificate of Analysis. Lot-specific COA and supporting records are available for qualified buyer review when appropriate. |
| Quality system | ISO 22000:2018, FSSC 22000, HACCP and GMP (certificates provided on request) |
| Supplier | Nutrition BioTech, 1601 W. Mission Blvd, Suite 103 (DL#29), Pomona, CA 91766, United States |
Pterostilbene (StilbElite™)
Pterostilbene for premium antioxidant and skin-longevity supplement formulas.
Why brands ask for it
StilbElite™ Pterostilbene gives brands a premium resveratrol-alternative story for skin longevity, antioxidant and healthy-aging products. It can be positioned for products that need a stronger polyphenol differentiation than commodity resveratrol.
Finished-product fit
Healthy aging, antioxidant, skin longevity, resveratrol upgrade. The strongest conversations start with format, serving size, documentation, and how the material behaves in the intended formula.
What makes the sample useful
- More lipophilic resveratrol analog story
- Premium low-dose polyphenol
- Fits skin and longevity stacks
Before the sample ships
- Confirm choose pterostilbene over resveratrol.
- Review serving-size logic and label-space fit.
- Confirm source, identity, and supporting documentation.
- Confirm active marker, assay method, and specification range.
- Confirm cholesterol concerns.
File Package
Ask for the material files that match your market, dosage form, and internal review process.
Available documents may include: COA / Specification / Allergen Statement / GMO Statement / Vegan Statement / Heavy Metals / Microbial Limits / Manufacturing Flow Chart / Residual Solvent / Country of Origin / Composition Statement.
Regulatory & Facility Support
Regulatory review notes for the target market can be provided. Nutrition BioTech does not hold and does not claim any GRAS notification or NDI notification for this material.
Facility and quality system support follows the same certificate set named in the specification table: ISO 22000:2018, FSSC 22000, HACCP and GMP. The holding entity for each certificate is named on the certificate and confirmed under buyer review.
Published research context
Pterostilbene has an extensive peer-reviewed literature. The studies below are provided as technical context for formulators evaluating this raw material. These entries summarise what the cited publications report. They are not claims about Nutrition BioTech material, and no health, therapeutic or cosmetic outcome is claimed or implied for any finished product. Buyers are responsible for the claims they make on their own labels and for confirming what is permitted in their market.
- Comparative oral pharmacokinetics against resveratrol in ratsReported that only low plasma concentrations of resveratrol were seen following oral administration, with rapid metabolism to glucuronide and sulfate conjugates, whereas after 14 days of equimolar oral dosing in rats the peak plasma concentrations of pterostilbene were about tenfold higher than those of resveratrol.Kapetanovic IM, Muzzio M, Huang Z, Thompson TN, McCormick DL. Cancer Chemotherapy and Pharmacology. 2011;68(3):593–601. PMID 21116625 — source
- HPLC-UV assay and pre-clinical pharmacokinetic parametersDescribed a validated HPLC-UV method measuring absorbance at 320 nm, linear over 20–2000 ng/mL with a limit of detection of 6.7 ng/mL and a lower limit of quantification of 20 ng/mL. Applied in rats, the method gave a terminal elimination half-life of 96.6 ± 23.7 min, clearance of 37.0 ± 2.5 mL/min/kg and an absolute oral bioavailability of 12.5 ± 4.7%.Lin HS, Yue BD, Ho PC. Biomedical Chromatography. 2009;23(12):1308–1315. PMID 19488981 — source
- Cyclodextrin complexation, phase solubility and solid-state characterisationReported AL-type phase-solubility profiles with α-cyclodextrin and β-cyclodextrin, corresponding to apparent solubility enhancements of about 100-fold and 40-fold respectively over the concentration range studied, with 1:1 stoichiometry confirmed by Job plots and apparent 1:1 stability constants of 1144, 4950 and 133 M⁻¹ for the α-, β- and γ-cyclodextrin complexes. The γ-cyclodextrin system gave a BS-type profile with observed precipitation. Complexes were characterised by DSC, TGA, FT-IR and X-ray diffraction.Catenacci L, Vicatos AI, Sorrenti M, Bonferoni MC, Caira MR. Pharmaceutics. 2022;14(1):8. DOI 10.3390/pharmaceutics14010008 — source
Specification FAQ
What is the CAS number for Pterostilbene?
The CAS number for Pterostilbene is 537-42-8. The molecular formula is C16H16O3 and the molecular weight is 256.30 g/mol. Machine-readable identifiers: InChIKey VLEUZFDZJKSGMX-ONEGZZNKSA-N · PubChem CID 5281727.
What purity is Pterostilbene supplied at, and by which method?
98% minimum by HPLC, stated on the Certificate of Analysis for each lot.
Is Pterostilbene soluble in water?
Practically insoluble in water; soluble in ethanol, DMSO and propylene glycol. Solubilised and dispersible formats should be discussed for liquid and beverage systems.
