Berberine supplier specification
Nutrition BioTech is a bulk berberine ingredient supplier and manufacturer, supplying berberine hydrochloride powder at 97% minimum by HPLC (CAS 633-65-8), plant-derived from Phellodendron and Coptis botanical sources, including micellized Pro-Micelle formats, for B2B nutraceutical and dietary-supplement formulation.
Every lot ships with a Certificate of Analysis stating identity, HPLC assay and the assay basis, from an ISO 22000 and FSSC 22000 certified quality system. Samples, specifications and COAs are available on request for formulation trials.
| Ingredient name | Berberine (supplied as berberine hydrochloride) |
|---|---|
| Synonyms | Berberine HCl; berberine chloride; berberine hydrochloride; protoberberine-class isoquinoline alkaloid |
| CAS number | 633-65-8 (berberine hydrochloride) |
| Molecular formula | C20H18ClNO4 (C20H17NO4 · HCl) |
| Molecular weight | 371.81 g/mol (hydrochloride) |
| Assay / purity | 97% minimum by HPLC (berberine hydrochloride). Micellized (Pro-Micelle) formats are specified per project; other grades available on request. |
| Production route | Botanical extraction and purification. Berberine is a protoberberine-class isoquinoline alkaloid; commercial material is typically obtained from Phellodendron and Coptis botanical sources. Botanical origin is stated in the lot documentation. |
| Appearance | Yellow crystalline powder |
| Solubility | Slightly soluble in water at room temperature; more soluble in hot water and in dilute ethanol. Micellized formats are supplied for water-dispersible applications. |
| Typical applications | Capsules, tablets, sachets and stick packs, powder blends, and micellized liquid or powder concepts for B2B dietary-supplement programs. |
| Documentation | Certificate of Analysis (identity and HPLC assay with assay basis), specification sheet, heavy metals, microbiological, residual solvents, allergen and GMO statements; stability data available on request. |
| Quality system | ISO 22000:2018, FSSC 22000 and HACCP based quality system, GMP-aligned manufacturing; certificates available on request. |
| Supplier | Nutrition BioTech, 1601 W. Mission Blvd, Suite 103 (DL#29), Pomona, CA 91766, United States |
Berberine Pro-Micelle / product-first metabolic route
Berberine Pro-Micelle: make berberine work harder than a capsule label.
Berberine already has market awareness. The next buyer question is whether the ingredient can support a better product experience: dispersion, routine fit, capsule burden, sensory direction, sample review, file package and claim-safe post-GLP-1 companion positioning.
Market reframe
The market knows berberine. That is the opening and the trap.
Another high-dose berberine story is easy to ignore. A stronger B2B route starts with the material, then asks how it behaves in real formats: wetting, dispersion, bitterness, powder flow, daily routine fit, and whether the brand can explain the product without risky disease or drug language.
Ingredient first
Start with Berberine Pro-Micelle as the material route, not a vague “solution” pitch.
raw materialsampleCOA/spec
Format second
Review sachet, stick pack, powder, capsule and routine-use fit before promising a launch path.
dispersiontasteroutine fit
Platform third
Connect the material to Post-GLP-1 companion concepts with protein, fiber, creatine or DHB only after the formula job is clear.
post-GLP-1sachet routeclaim review
Best-fit applications
Where Berberine Pro-Micelle fits
- Post-GLP-1 companion sachets with protein, fiber, creatine or other muscle / gut / metabolic routine ingredients.
- Metabolic-wellness capsules where commodity berberine needs a better format and consumer-experience story.
- Stick packs and powders where dispersion, residue, taste direction and usage ritual matter.
- Brand teams comparing berberine, DHB and broader gut-metabolic platform routes.
Buyer review checklist
What a serious buyer should review before choosing a berberine route
Format behavior
- Dispersion and wetting behavior in the intended format.
- Residue, clumping, bitterness and sensory direction.
- Capsule burden versus sachet / stick pack routine fit.
File package
- COA/spec and assay method.
- Heavy metals, microbial limits and residual solvent files as applicable.
- Allergen, GMO and vegan statements as applicable.
Launch language
- Supplement-safe metabolic wellness language.
- Post-GLP-1 companion wording with clear supplement-category positioning.
- Claim boundary support for sales, website and packaging review.
Connected route
Pair Berberine Pro-Micelle with DHB Pro-Stable when the formula needs a sharper upgrade path.
Berberine Pro-Micelle opens the category conversation around dispersion and routine fit. DHB Pro-Stable supports the technical upgrade conversation around stability, bitterness, color, packaging and file-package discipline.
Together, they can support a more serious post-GLP-1 companion platform discussion without turning the public page into a drug-comparison or disease claim.
FAQ for brand teams
Berberine Pro-Micelle FAQ
How should this sit next to post-GLP-1 programs?
Use it as a companion ingredient route for metabolic wellness routines, format review, sample planning and claim-safe product development. Keep public language focused on supplement positioning and application fit.
Is this only for capsules?
No. The stronger buyer conversation is format-specific: capsules, powders, sachets and stick packs each need different review of dispersion, taste, dose, packaging and claim language.
What should a buyer request first?
Ask for sample availability, COA/spec, assay method, dispersion or application notes where available, sensory direction, file package and claim-boundary support.
Bring the format, not just the ingredient name.
Nutrition BioTech can review Berberine Pro-Micelle against the target application, sample path, file package and public claim boundary before your brand commits to a formulation.
