5-HTP (Griffonia simplicifolia seed extract) supplier specification
Nutrition BioTech is a bulk 5-HTP ingredient supplier and manufacturer, supplying Griffonia simplicifolia seed extract standardized to 20–98% 5-hydroxytryptophan (CAS 4350-09-8) by HPLC, for B2B nutraceutical formulation.
The wide standardization range is deliberate: a 20% Griffonia extract and a 98% 5-HTP grade behave very differently in label space, cost and blend design, so the assay grade is chosen per project rather than fixed. Every lot ships with a Certificate of Analysis stating botanical identity, HPLC assay and the assay basis.
| Ingredient name | 5-HTP, supplied as Griffonia simplicifolia seed extract standardized to 5-hydroxytryptophan |
|---|---|
| Synonyms | 5-HTP; L-5-hydroxytryptophan; oxitriptan; Griffonia seed extract; 5-hydroxy-L-tryptophan |
| CAS number | 4350-09-8 (L-5-hydroxytryptophan) |
| Molecular formula | C11H12N2O3 |
| Molecular weight | 220.22 g/mol |
| Assay / purity | Standardized from 20% to 98% 5-HTP by HPLC. The exact assay grade is specified per order and stated on the Certificate of Analysis for each lot. |
| Source / production route | Seed of Griffonia simplicifolia (Baill.), West and Central Africa; extraction and purification, with the solvent system stated on the specification sheet. |
| Appearance | Off-white to light beige or tan powder; shade depends on assay grade |
| Solubility | Slightly soluble in water and improves on warming; solubility of standardized extracts varies with assay grade. |
| Typical applications | Capsules, tablets, powder blends and stick packs for B2B nutraceutical manufacturing; commonly formulated alongside magnesium, L-theanine and GABA |
| Documentation | Certificate of Analysis, specification sheet, botanical identity, heavy metals, microbiological testing, residual solvents, pesticide residues, allergen statement, GMO statement and stability data |
| Quality system | ISO 22000:2018, FSSC 22000, HACCP and GMP (certificates provided on request) |
| Supplier | Nutrition BioTech, 1601 W. Mission Blvd, Suite 103 (DL#29), Pomona, CA 91766, United States |
5-HTP 20-98%, Griffonia Seed Extract
Griffonia-derived 5-HTP for sleep, calm mood and nighttime wellness formulas with flexible assay options.
Why brands ask for it
Nutrition BioTech supplies Griffonia Seed Extract standardized to 5-HTP for brands developing sleep, stress-support and mood-balance products. The ingredient is suitable for capsules, tablets, blends and nighttime formulas where buyers need assay flexibility, COA/spec support and clean supplement positioning.
Finished-product fit
Sleep quality, calm mood, emotional eating support, stress-night formulas. The strongest conversations start with format, serving size, documentation, and how the material behaves in the intended formula.
What makes the sample useful
- Standardized 5-HTP assay range
- Sleep/mood stack compatibility with magnesium, L-theanine, GABA
- Botanical seed-origin story
Before the sample ships
- Confirm source, identity, and supporting documentation.
- Confirm active marker, assay method, and specification range.
- Match the material to the target capsule, tablet, sachet, gummy, or powder format.
- Request allergen, GMO, vegan, and source statements.
- Review serving-size logic and label-space fit.
File Package
Ask for the material files that match your market, dosage form, and internal review process.
Available documents may include: COA / Specification / Allergen Statement / GMO Statement / Vegan Statement / Heavy Metals / Microbial Limits / Manufacturing Flow Chart / Residual Solvent / Country of Origin / Composition Statement.
Regulatory & Facility Support
Product-specific regulatory information may include Self-GRAS, NDI/NDIN, GRAS, ODI, or regulatory review notes, depending on the ingredient and target market.
Facility and quality system support may include Kosher, Halal, HACCP, ISO 22000, PCQI, c-GMP, NSF and other applicable certificates upon request.