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From Lab to Clinic: Pterostilbene Microcapsules Enable More Precise and Efficient Anti-Inflammation

Views: 1000     Author: Site Editor     Publish Time: 2025-09-16      Origin: Site

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From Lab to Clinic: Pterostilbene Microcapsules Enable More Precise and Efficient Anti-Inflammation

In recent years, intestinal health and inflammation management have gradually become research hotspots in the fields of nutrition and medicine. Ulcerative Colitis (UC), as a type of chronic inflammatory bowel disease, has seen a continuous rise in its global prevalence. Existing drug therapies (such as aminosalicylic acid, hormones, immunosuppressants, and biological agents) often have limitations including insufficient efficacy or obvious side effects. Therefore, there is an urgent need for new intervention solutions that are safe, effective, and highly targeted.


The latest study published in Engineering (IF 11.6), a journal of the Chinese Academy of Engineering, has brought new breakthroughs to address this challenge:

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Pterostilbene (PSB) is a natural polyphenol that inherently possesses excellent anti-inflammatory, antioxidant, and immunomodulatory effects. However, its low oral bioavailability has long been a shortcoming restricting its clinical application.


To overcome this pain point, the research team innovatively adopted microfluidic electrospray technology to load pterostilbene into prebiotic microcapsules (PSB@MC), successfully achieving the precise delivery of pterostilbene to the colon.


Experiments have shown that PSB@MC can not only effectively improve the intestinal microenvironment, reduce the release of pro-inflammatory factors, and restore the intestinal barrier homeostasis, but also further enhance the body's own intestinal defense function by activating the AHR/IL-22 signaling pathway. This achievement clearly indicates that the combination of natural active substances and prebiotic delivery systems will be an important development direction for future nutrition and health as well as adjuvant disease treatment.

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As an enterprise long dedicated to the development of anti-aging and intestinal health raw materials, we have always paid close attention to the application potential of pterostilbene and its derivatives, and have already made in-depth layouts in related fields:


  1. Raw Material End: We have established a green synthesis process for high-purity pterostilbene and a strict quality control system to ensure the stability and safety of raw materials from the source;

  2. Delivery End: We are actively exploring a variety of innovative solutions such as liposomes, nanocapsules, and prebiotic carriers to continuously improve the targeting and bioavailability of active substances;

  3. R&D End: Focusing on the direction of intestinal health, we have established in-depth cooperation with a number of scientific research institutions to fully promote the functional verification, clinical research, and achievement transformation of raw materials.


The latest research on pterostilbene prebiotic microcapsules has brought new ideas for solving problems in the fields of intestinal health and inflammation management. In the future, we will continue to take science as the cornerstone, deepen the innovative application and evidence-based research of raw materials, and strive to provide safer, more efficient, and more clinically valuable solutions for the global nutrition and health industry.




Important Reminder: All content in this article is for general reference only and is provided solely to offer information support for practitioners in the nutrition and health industry. Descriptions related to efficacy are supported by corresponding data, but they do not represent claims or guidance for consumers. Content related to health, medical care, and technological applications is for reference only. For medical matters, please consult professional medical institutions and follow medical advice. This article does not provide any medical recommendations.


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